This is definitely good news for all diabetes patients as a team of US scientists have developed a new insulin pill that could make diabetes treatment ‘painless’. It is an oral method of administering the insulin that can be a less painful alternative to millions of people worldwide with diabetes that has to inject them with the drug to manage their blood-sugar levels. Scientists have successfully encapsulated insulin using Cholestosomes, a neutral and lipid-based particle that can be administered orally with tiny vesicles that can deliver insulin where it needs to go without injecting. The biggest obstacle to delivering insulin orally is ushering it through the stomach intact. Proteins such as insulin are no match for the harsh, highly acidic environment of the stomach. They degrade before they get a chance to move into the intestines and then the bloodstream where they’re needed, the study said. However, the new vesicles that are made of naturally occurring lipid molecules are normal building blocks of fats, the researchers said, adding that they are unlike other lipid-based drug carriers, called liposomes. Lead researcher Mary McCourt, Professor at Niagara University in New York, US,”Most liposomes need to be packaged in a polymer coating for protection.
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